Biochemistry

Shree Sai Prakashan is writing a full set of B.Pharm titles to this new NEP 2020 syllabus. Get notified the moment the book for this subject is released, or pre-book sets for your college.

Unit 1 · Enzymology 10 hrs

Properties, nomenclature and IUB classification of enzymes and coenzymes; enzyme kinetics (Michaelis–Menten and Lineweaver–Burk plots); enzyme inhibitors and regulation (induction, repression, allosteric); therapeutic and diagnostic applications of enzymes and isoenzymes; vitamins and minerals; and clinical chemistry — liver and renal function tests.

Unit 2 · Bioenergetics & Carbohydrate Metabolism 10 hrs

Introduction to biomolecules; bioenergetics and energy-rich compounds (ATP, GTP); carbohydrate metabolism — glycolysis, the citric-acid (TCA) cycle, gluconeogenesis, the HMP shunt and glycogen metabolism, blood-glucose regulation and derangements in diabetes mellitus; and biological oxidation — the electron transport chain and oxidative phosphorylation.

Unit 3 · Lipid Metabolism 7 hrs

Classification and functions of lipids and lipoproteins (HDL, LDL, VLDL, chylomicrons); β-oxidation and de-novo synthesis of fatty acids and ketone bodies; cholesterol and the lipid profile; and disorders — hyperlipidaemia, atherosclerosis, fatty-liver disease and obesity.

Unit 4 · Amino Acid & Protein Metabolism 10 hrs

Classification and functions of amino acids and proteins; transamination, deamination, decarboxylation and the urea cycle; catabolism of phenylalanine and tyrosine and related disorders (phenylketonuria, albinism, alkaptonuria); neurotransmitters and hormones derived from amino acids; and heme catabolism and jaundice.

Unit 5 · Nucleic Acid Metabolism & Genetic Information 8 hrs

Biosynthesis and catabolism of purine and pyrimidine nucleotides, hyperuricaemia and gout; genome organization and the central dogma — DNA replication, transcription and translation; the genetic code and inhibitors of transcription and translation; and DNA damage and repair.